Selective Intra Arterial Infusion Chemotherapy for Malignant Nasal and Paranasal Sinus Tumors

概要

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Since 1998, we have treated 14 malignant nasal and paranasal sinus tumor patients with selective intra arterial infusion chemotherapy. We report results for 7 of maxillary sinus, 3 of sphenoid sinus 1 of ethmoid sinus, and 3 of the nasal cavity. Only 1 maxillary sinus case involved recurrence. Intra arterial infusions of cisplatin (100mg/body) was delivered rapidly to the tumor and usually repeated for 4 times. Conventional externalbeam irradiation (2Gy per fraction×30) was also used. Complete response cases were 9 of 14 and control of the local lesion found in all new cases.These results indicate that Intra arterial infusion therapy is effective against advanced malignant nasal and paranasal sinus tumors.
日本鼻科学会の論文