Heat Effect of Free Electron Lasers on Cholesteryl Oleate.
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概要
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We demonstrated selective removal of cholesteryl oleate which is specifically accumulated in the arteriosclerotic region on the arterial walls. To discuss what mechanisms are there in effects which were induced by infrared free electron lasers (FEL), we compared FEL exposure effects and heating effects. FEL exposure experiments were carried out using wavelength of 5.75μm and several average power (2-15 mW). The FEL exposure induced melting and decrease of ester bonds. Using the values of absorbed 1FEL-macropulse energy for each power densities, temperature was estimated to be 50-300°CIn the heating experiments, the sample was heated from room temperature to 500°CMelting and carbonization were observed at 50°C and 300°C respectively. We found that melting is induced by both of the FEL exposure and the heating, structural changes and ablation are induced only by the FEL exposure, and that carbonization are not induced by the FEL exposure but by the heating.
- 社団法人 レーザー学会の論文
社団法人 レーザー学会 | 論文
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