Evaluation of the Contents of Antifungal Agents Allowed as Food Additives in Foods and the Daily Intake Deduced from the Results of the Official Inspection in Japan in Fiscal Year 1994:Concentration of Food Additives in Foods and the Daily Intake in Japan

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• The concentrations of antifungal agents permitted as food additives (diphenyl, imazalil, o-phenylphenol and thiabendazole) in foods sold in Japan were estimated using the results of the official inspection in fiscal year 1994 by 74 local governments. The total number of inspection samples was 6, 633 including 289 domestic foods. The detection rates of diphenyl, imazalil, o-phenylphenol and thiabendazole in foods in which the use of these antifungal agents is permitted were 2.7%, 41.5%, 29.1% and 47.0%, respectively. The mean concentrations of these antifungal agents in the whole body of citrus fruits in all tested samples in which their use is permitted were 0.3%, 12.2%, 3.9% and 9.5% of the legal maxima, respectively. Imazalil in the whole body of bananas was 0.2% of the limit, and thiabendazole in the whole banana and banana flesh was 0.2% and 0.5% of each limit, respectively. Some antifungal agents were detected in some processed foods in the category of marmalade and jam.The estimated daily intakes of these antifungal agents were 2.64, 8.77, 14.1 and 34.5μg/person, respectively, calculated from the mean concentrations in foods (including peel of citrus fruits) obtained in the present study when foods containing an undetectable level (below the detection limit) were presumed to contain 0mg/kg and utilizing the food consumption levels reported by the "Investigation Group of the Daily Intake of Food Additives in Japan in fiscal year 1994". The estimated daily intake of these antifungal agents was less than 0.7% of the Acceptable Daily Intake (ADI). Citrus fruits contributed more than 97.4% of the daily intake of imazalil, o-phenylphenol and thiabendazole, and 75.4% of that of diphenyl. The estimated daily intakes were 11.9, 10.3, 16.6 and 39.5μg/person, respectively, when foods with undetectable levels of the agents were presumed to contain these agents at concentrations equal to the detection limit. Even in this case, the values were not more than 0.8% of the ADI.

• 公益社団法人 日本食品衛生学会の論文

公益社団法人 日本食品衛生学会 | 論文

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• 容器入り飲用水中の無機陰イオン濃度
• 食物アレルギーに関する食品表示とリスクコミュニケーション
• 植物性の健康食品の安全性について
• 肝蛭駆除剤(トリブロムサラン, オキシクロザニドおよびブロムフェノホス)の乳牛への投与後の血漿中濃度および乳汁への移行

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