A Resected Case of Solitary Pulmonary Mucormycosis Showing Peculiar Histological Findings Without Significant Predisposing Factors.

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A resected case of an asymptomatic, solitary nodule in the lower lobe of the right lung due to mucormycosis is reported. A healthy 50-year-old man was first found to have a pulmonary nodule during by an annual health examination. Right lower lobectomy was performed on suspicion of a malignant neoplasm. The surgical specimen revealed a yellowish-white, necrotizing tumor approximately 4.0cm in diameter. Histologically, many foreign body granulomata around central abscesses were observed, surrounded by extensive lympho-plasmacytic infiltration. Scattered irregular-shaped, non-septated, eosinophilic fungal elements were present in the abscess and granulomata. Immunohistochemically, the fungal elements were stained positively with anti-Rhizopus oryzae antibody.This was a case of mucormycosis in a healthy person.
日本医真菌学会の論文