T. rubrum isolated with griseofulvin resistant granuloma trichophyticum.
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概要
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We reported earlier on a 59-year-old man with generalized granuloma trichophyticum caused by Trichophyton rubrum (Mycopathologia, 82, 77-82, 1983).Since the definitive diagnosis of generalized granuloma trichophyticum was made, the patient was treated with griseofulvin, and the multiple cutaneous nodules, indurative plaques and ulcers apparently disappeared. But a few years later, ulcers recurred and developed on his right axilla, back and left upper extremity. A biopsy specimen taken from the ulcers was cultured on Sabouraud's dextrose agar. Colonies from the specimen grew at 37°C but were not successful grown at room temperature within two weeks. This isolate had no sensitivity to griseofulvin, but did have sensitivity to ketoconazole, and the patient was completely healed by using oral ketoconzaole.
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