A case of endogenous endophthalmitis due to Candida albicans.

概要

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Although incidences of mycosis have significantly increased lately in the ophthalmologic field, it is fairly rare to encounter a case other than mycotic keratitis.Recently, however, an autopsy case of a 25-year-old-male was diagnosed as acute disseminated encephalomyelitis. During the course of treatment with antibiotics and steroid hormones, it was strongly suspected that he had fungal endophthalmitis in bilateral eyes. A fungal culture taken from the intraocular abscess of the right eye at the time of autopsy was negative. However, histologic examination showed an acute suppurative inflammation accompanying granulation tissues around the lesion. A few scattered candidal elements were found in the lesion by PAS reaction and immunohistological examination. The condition was diagnosed as endogenous fungal endophthalmitis, its histogenesis was discussed and relevant literature was reviewed.Administration of antibiotics followed by abdominal surgery and a large quantity of steroid hormones is considered to have strongly related to the onset of this disorder. However, contrary to the Wests, it is very uncommon in Japan to encounter such a case with an onset obviously related to steroid hormones.
日本医真菌学会の論文