Symposium Immuno-Biochemical Aspects of Host Defense Mechanisms against Fungal Infection Introduction
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概要
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Numerous reports, but contradictory each other, have appeared in the literature on the defense mechanisms of the host against fungal infection. This symposium was organized in an attempt to systematize these results from the view point of immuno-biochemistry. With reference to the infection of dermatophytes, the relationship between invasion sites and tissue chemical components, including keratinase inhibitors, was discussed. As for opportunistic fungal infection, sensitization or immunization of the host and the development of the specific symptoms were described with Aspergillus fumigatus and Candida albicans. Autoptic as well as clinical studies on fungal infection were also reported with respects to peripheral leukocyte counts and levels of immunoglobulins. Finally, strong protective immunity elicited by purified ribosome fraction from Histoplasma capsulatum and its effectiveness against the infection was emphasized.
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