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The statistical survey was performed on the inpatients with cryptococcal infection at Kyushu University Hospital during the period from 1975 to 1979. In the studied period 18 cases of cryptococcosis were recorded, and 2 to 6 cases per annum were detected. In the whole group 11 men and 7 women were affected, and their mean age was 50 (range 15-84). Forteen cases of them were considered as a possible hospital-acquired cryptococcosis. The main predisposing conditions were malignant lymphoma and leukemia. The mortality in the possible hospital-acquired cryptococcosis was 86 per cent (12/14 cases) with a high rate of relapse. The figures reported here emphasize that cryptococcosis should be regarded as one of the main opportunistic fungal infections.
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