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A crude toxin fraction has been isolated from mycelia and culture filtrates of Aspergillus fumigatus, and some biological properties such as dermonecrotic, hemorrhagic, hemolytic and lethalitic activities were found in the crude toxin. A hemolytic toxin (Asp-hemolysin) was purified from the fraction. Physical, chemical and biological characteristics were investigated in the hemolytic toxin. The hemolytic toxin production was studied by using different culture conditions and several strains. The hemolytic activity of Asp-hemolysin was inhibited specifically by Hg2+, and could be restored by addition of SH reagents. Another many characteristics of the hemolysin were discussed in comparisonn with those in bacterial hemolvsins.
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