Macrophage Migration Inhibition Test on Experimental Candidiasis
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概要
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Much attention has paied to cellular immunity in microbial infection. On mycotic infection, many clinical case reports suggest that the immunity would be due to cellular immunity in which the thymus dependent lymphocytes (T-cell) are principally involved and play a major role in protective immunity. In order to make clear the relationship between the mycotic infection and cellular immunity, we studied on the experimental candidiasis in immunosuppressive animals administering azathioprine, predonisolone or anti-lymphocyte serum (ALS). In such animals, the virulence of Candida albicans amplified, Macrophage Migration Inhibition Test (MIT) and Delayed Type Hypersensitivity (DTH) for Candida specific antigen showed a little response. The defects of these responses on sensitized lymphocyte cause much damage to the registance to infection.
- 日本医真菌学会の論文
日本医真菌学会 | 論文
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