Production of aflatrem and its related indoloditerpenes by microsclerotium-producing strains of Aspergillus flavus
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概要
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The production of aflatrem and its related indoloditerpene metabolites by microsclerotium-producing strains of Aspergillus flavus was investigated. Four strains of atypical A. flavus isolated from Indonesian traditional medicines (native name, "Jamu") and three representative strains of the same fungus obtained from the Northern Regional Research Center, USDA were cultured on Czapek-Yeast extract Agar at 34°C and the amounts of tremorgenic mycotoxins, aflatrem and seven related indoloditerpenes, were measured by high-performance liquid chromatography with a UV detector. All the strains examined produced aflatrem and dihydroxyaflavinine. The concentrations of them were ranged from 149 to 3, 009 and 1, 092 to 35, 629μg/g of the dried sclerotia, respectively. Aflavinine, monohydroxyaflavinine, monohydroxyisoaflavinine, paspaline, paspalinine and emindole SB were detected in the sclerotia of A. flavus. This is the first report on the production of emindole SB and paspaline by A. flavus.
- 日本マイコトキシン学会の論文
日本マイコトキシン学会 | 論文
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