Studies on T-wave and QT interval in Beagle Dogs.
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Electrocardiograms (ECG) in limb leads were recorded from 100 beagle dogs (6-40 months old, weighing 7.0-12.0 kg) in the right lateral recumbency without anesthesia, and the T wave, variation of the QT intervals, and a correlation between the QT and RR intervals were investigated.<BR>1. The patterns of T waves were variable, which included positive, negative, notched, biphasic and flat. In one dog, the pattern of T wave changed from positive to biphasic, and then turned back to positive during short time.<BR>2. Among 96 dogs, the high and positive T waves were found mainly in leads II, III and aVF, and the negative ones in leads I, aVR and aVL.<BR>3. Time-dependent variation of the RR and QT intervals were examined in the ECG taken from 4 dogs over 2-4 min on 2 successive days. In 2 of 4 dogs, the RR intervals gradually prolonged with time ; however, in the remaining 2 dogs RR intervals did not change throughout the recording period. The QT intervals gradually prolonged with time in all 4 dogs.<BR>4. It was found that the QT and RR intervals were not always well correlated in each dog; when 1000 pairs of the QT and RR intervals were compared in ECG taken from 4 dogs over 2-4 min on successive 5-7 days. The coefficient of correlation between the mean QT and RR intervals of 4 dogs over 4-8 sec was greater than that from the individual values in each ECG.<BR>As mentioned above, the patterns of T waves were considerably variable in dogs, and the QT intervals can also change within a short time. These findings suggest that more detailed examinations on the T wave and QT-interval are necessary to take up the QT interval as a diagnostic parameter in dogs.
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