Statin trial for secondary prevention of ischemic stroke: J-STARS:J-STARS
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概要
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The Japan Statin Treatment Against Recurrent Stroke (J-STARS) Study is a prospective, randomised, open, blinded endpoint study designed to evaluate the effects of pravastatin 10 mg/day in patients who preveously experienced an ischemic stroke other than cardioembolic infarction, but who do not have any CHD requiring statin treatment. We planed to enroll a total of 3, 000 patients. aged 45-80 years who have serum cholesterol level of 180-240 mg/dl. The primary endpoint is fatal and non-fatal stroke recurrence during the follow-up period of 5 year and the data collection phase of the study is expected to be completed by April 2010. Effects of statin on hs-CRP and carotid intima-media thickness will also be investigated as substudies of J-STARS. Further, we planned a longitudinal follow-up study called J-STARS-L (J-STARS-Longitudinal), where we aquired a follow-up data from the stroke data bank developed by the Japan Standard Stroke Registry Study (JSSRS) Group, and attempted to confirm the proposed cardiovascular event rate in the ischemic stroke patients who should be enrolled in J-STARS. The present status of J-STARS-L and J-STARS have been presented in this symposium.
- 一般社団法人 日本脳卒中学会の論文
一般社団法人 日本脳卒中学会 | 論文
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