Multimodal evoked potentials in patients with multi-infarct dementia and Alzheimer's disease.
スポンサーリンク
概要
- 論文の詳細を見る
The auditory event-related potential (ERP), somatosensory evoked potentials (SEP), visual evoked potential (VEP) and brainstem auditory evoked potential (BAEP) were studied in 15 patients with Alzheimer's disease (AD), 16 patients with multi-infarct dementia (MID) due to subcortical infarctions and 15 normal control subjects. Both groups with dementia showed significant prolongation of the N200 and P300 latencies of the ERP as compared with those of the normal controls. In addition, patients with AD revealed significant prolongation of the P200 latency. Patients with MID showed significant prolongation of N13-N20 and N20-P40 of the SEP as compared with the normal controls, while patients with AD revealed only significant prolongation of N20-P40. There were no significant differences in P100 latency of the VEP among the three groups. The interpeak latencies between the I and V waves of the BAEP in patients with AD and MID were significantly longer than that of the normal controls. Thus, electrophysiological differences between MID and AD were noted in the ERP and SEP. The present results indicate that these two diseases with dementia exhibit abnormalities of evoked potentials, and also have some electrophysiological differences, which may be related to the underlying pathogenetic mechanisms. Measurement of multimodal evoked potentials, particularly of the SEP and ERP, may be helpful for the differential diagnosis of AD and MID.
- 一般社団法人 日本脳卒中学会の論文
一般社団法人 日本脳卒中学会 | 論文
- Two cases with aphasia in the left putaminal damage and one case with visuospatial neglect in the right putaminal damage
- Alterations of plasma von Willebrand factor activity and the influence of anti-platelet drugs in acute cerebral infarction
- Carotid endarterectomy plaques correlation of clinical events and morphology.
- Stenting for stenosis of major cerebrovascular arteries.
- Cerebral infarction following antihypertensive therapy.