The utility of EMIT for toxicology screening for use in an emergency room.
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概要
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The results of toxicology screening of samples from 507 patients admitted to the Critical Care Medical Center (CCMC) of Nippon Medical School during a 10-month period (from Oct. 1992 to Jan. 1993 and from Jun. 1993 to Dec. 1993) were discussed. We investigated the actual condition of drug-use in patients by using an immunoassay, EMIT, and the results were confirmed by gas chromatography/mass spectrometry. Blood samples were analyzed for ethylalcohol (EtOH) by head space gas chromatography. Of the 507 patients, 42.7% (53) were positive for EtOH. Twenty-four point five percent (124) were positive for one or more drugs by EMIT: amphetamines (29), opiates (6), cannabinoids (2), barbiturates (18), benzodiazepines (65), tricyclic antidepressants (4). False-positive reactions caused by cross-reactivity with the analog were found in both the amphetamine and opiate assays. There were no falsenegative reactions in any of the assays. Rapid, random toxicology screening can provide useful clinical information for the patients admitted to a CCMC, especially for patients who were injured and sustained unknown-etiology disturbances. It is concluded that EMIT is suitable for toxicology screening for use in an emergency room.
- 一般社団法人 日本救急医学会の論文
一般社団法人 日本救急医学会 | 論文
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