Presence of Vasotocin Receptors in the Anterior Pituitary of Chicken.
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概要
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Crude cell membrane fractions of cephalic and caudal lobes of the anterior pituitary of chickens were obtained, and binding to 125I•arginine vasotocin (AVT) were examined. In both lobes, the binding to 125I•AVT was specific and saturable. Equilibrium dissociation constant (Kd) and maximum number of binding sites (NBSmax) estimated by the Scatchard analysis were the order of 10-10M and the value of 10-13moles per mg protein, respectively. Although the value of the Kd was not different, the NBSmax value in laying hens was higher than that in cocks and also was higher in caudal lobes than in cephalic lobes. The results suggest that AVT receptors are present in the anterior pituitary of chickens.
- 日本家禽学会の論文
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