Plasma levels of arginine vasotocin in the hen before and immediately after premature oviposition induced by prostaglandins and arachidonic acid.
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Arginine vasotocin (AVT) levels in plasma shortly after premature oviposition induced by intrauterine injection of prostaglandins (PGs) (PGE1, PGE2 and PGF2α) and arachidonic acid were measured in the laying hen. The injection of PGs and arachidonic acid evidently led to premature oviposition when injected 15-17 h and 2-3 h before the expected time of oviposition, being coincided with a significant (P<0.01) increase in plasma AVT level. PGF2α was most effective in eliciting premature oviposition, resulting in higher level of plasma AVT. A significant (P<0.01) increase in plasma AVT was also observed even when oviposition was not caused by PGF2α injection, though the level of AVT was slightly lower than that in the case of induced oviposition. The arachidonic acidinduced oviposition was blocked by pretreatment with indomethacin, and plasma AVT level of treated hens 5 min after the injection of drug increased slightly but not significantly. The results obtained from this experiment suggest that the increase in plasma AVT level may be associated with the production of the uterine PGs, causing an enhancement of uterine contractility.
- 日本家禽学会の論文
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