Effect of dietary pyrimethamine on hatchability and a recommendation on a procedure to check teratogenicity by hatchability.
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概要
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Teratogenic effect of pyrimethamine at dietary levels of 0, 5, 10, and 20ppm was examined. Fertile eggs obtained by feeding the experimental diets to laying White Leghorn hens, were set in an incubator. Fertility, early and late mortality of the embryos, hatchability and incidence of the deformed chicks were tested. Pyrimethamine up to 20ppm had little effect on feed intake, body weight gain, egg production and fertility, but had significant effects on mortality of the embryos, incidence of deformed chicks and hatchability. A linear dose-response relationship was observed between the dose of pyrimethamine and late mortality of the embryos, incidence of deformed chicks, and hatchability.A procedure of the hatchability test to examine teratogenicity of feedstuffs is recommended
- 日本家禽学会の論文
日本家禽学会 | 論文
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