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Two lines of chickens selected for GVHR competences were compared for the immune response to SRBC. The H line, which had higher GVHR competence, showed higher antibody production to SRBC in primary and secondary responses than did the L line, which had lower GVHR competence. The line differences of the immune response were found to be due mainly to IgG antibody production. However, the line differences of the IgM titers and the number of IgM antibody forming cells were not significant statistically.Possible associations of the B genotypes and the antibody titers to SRBC were not revealed. By comparison of the number of IgM antibody forming cells a tendency of B9/B9 >B9/B11>B11/B11 was showed, though the differences were not significant. Since the tendency was differed from that of immune response to other antigens, such as GRBC, DNP, or BSA, the antigen-specific genetic control associated with the MHC-B locus was suggested.In the analysis of SRBC-rosette forming cell percentage in peripheral lymphocytes the L line showed significantly higher percentage than did the H line. However, the differences among the B genotypes were not significicant.
日本家禽学会の論文