Two Cases of Inflammatory Pseudotumor of the Spleen.
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概要
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Inflammatory pseudotumor of the spleen is a tumorous lesion histologically characterized by infiltration of inflammatory cells and repair of interstitial tissue. Recently we experienced two patients with the disease, including the first patient in whom we failed to make the preoperative diagnosis and the second patient in whom the experience with the first patient led us to have a strong suspicion of the disease before a splenectomy. In both patients, an asymptomatic splenic mass was incidentally detected by an abdominal ultrasonography (US) at a medical check-up. The first patient was a 79-year-old man, whose abdominal US and CT revealed a solitary mass 49×40mm in size in the splenic hilus. Gallium Scintigraphy showed uptake in the mass of the spleen. Malignant lymphoma was suspected and a splenectomy was performed. Photomicrography showed an increase in fibroblasts and lymphocytes, and coagulative necrosis in the center. The tumor was histologically diagnosed as an inflammatory pseudotumor of the spleen. The second patient was a 67-year-old woman, who was incidentally found to have a splenic mass on abdominal US 3years earlier. Abdominal US was performed once a year and the splenic mass was found growing. CT and magnetic resonance imaging revealed a splenic mass 50mm in diameters, but no definite diagnosis was made. Based on our experience with the first patient and the diagnosis by exclusion, an inflammatory pseudotumor in the spleen was most likely. Splenectomy was performed and the tumor was histologically diagnosed as inflammatory pseudotumor of the spleen. It may be possible to make the preoperative diagnosis of the disease to some degree, if the presence of it is kept in mind like in the second patient.
- 日本臨床外科学会の論文
日本臨床外科学会 | 論文
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