CLINICAL STUDY OF POSTOPERATIVE CARDIOVASCULAR FUNCTIONS IN SEVERE ABDOMINAL INFECTION AND LIVER CIRRHOSIS

概要

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Cardiovascular functions in severe abdominal infection and liver cirrhosis were studied using a Swan-Ganz catheter. The multivariable data sets obtained by several physiologic studies in 12 patients with severe abdominal infection, 32 patients with liver cirrhosis, and 11 patients with esophageal cancer as a control group were examined. Both the patients with infection and liver cirrhosis frequently had increased cardiac output and diminished vascular tone with inefficient oxygen extraction. These so-called hyperdynamic states were more often found in the cirrhotics than the patients with infection. The oxygen consumption was significantly impaired in the patients with infection in the hypodynamic state or in the immediate postoperative period, when the peripheral cells might be damaged. This study showed that the charasteristics of cardiovascular functions in the patients with infeciton and the cirrhotics were often similar, but the difference appeared in oxygen usage, probably due to damage in the oxidative pathways of peripheral cells.
日本臨床外科学会の論文