Cellular Requirements for CRM 1 Import and Export
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概要
- 論文の詳細を見る
We studied the cellular requirements for the translocation of CRM 1 (exportin 1) between the nucleus and the cytoplasm. CRM 1 import requires neither ATP, Ran, Ran-dependent GTP hydrolysis, nor a particular temperature. CRM 1 and importin β compete with each other during their import. Thus, CRM 1 is able to enter the nucleus in a manner similar to importinβ. In contrast, the in vivo export of CRM 1 involves ATP-consuming step (s).
- 社団法人 日本生化学会の論文
著者
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Yamada Masami
Department Of Gastroenterology Hamamatsu Medical Center
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Shida Hisatoshi
Department Of Molecular Virology Institute For Genetic Medicine Hokkaido University
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Mabuchi Naoto
Department Of Molecular Virology Institute For Genetic Medicine Hokkaido University
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Zhang Xianfeng
Department Of Mechanical Engineering Tsinghua University
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