The Ubiquitin System: Deubiquitinating Enzymes as Cellular Regulators

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概要

• 論文の詳細を見る

• Modification of proteins by the covalent attachment of ubiquitin is a key regulatory mechanism of many cellular processes including protein degradation by the 26 S proteasome. Deubiquitination, reversal of this modification, must also regulate the fate and function of ubiquitin-conjugated proteins. Deubiquitinating enzymes catalyze the removal of ubiquitin from ubiquitin-conjugated substrate proteins as well as from its precursor proteins. Deubiquitinating enzymes occupy the largest family of enzymes in the ubiquitin system, implying their diverse function in regulation of the ubiquitin-mediated pathways. Here we explore the diversity of deubiquitinating enzymes and their emerging roles as cellular regulators.

• 社団法人 日本生化学会の論文

著者

• Park Kyung

  Nrl Of Protein Biochemistry School Of Biological Sciences Seoul National University

• Chung Sung

  Nrl Of Protein Biochemistry School Of Biological Sciences Seoul National University

• Bang Oksun

  Nrl Of Protein Biochemistry School Of Biological Sciences Seoul National University

• Chung Chin

  Nrl Of Protein Biochemistry School Of Biological Sciences Seoul National University

• Kim Jung

  Nrl Of Protein Biochemistry School Of Biological Sciences Seoul National University

関連論文

• Deubiquitinating Enzymes as Cellular Regulators
• The Ubiquitin System: Deubiquitinating Enzymes as Cellular Regulators

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