Antibacterial and Antifungal Activities of Tryptanthrin Derivatives
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概要
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Tryptanthrin (T) and 13 of its derivatives (T2NH2, T2Cl, T2Br, T2NO2, T8OMe, T8Me, T8F, T8Br, T8NO2, T2NH28OMe, T2NH28NO2, T2Br8Br, and T2NO28NO2) were synthesized, and their antimicrobial activities against a gram-positive bacterium (methicillin-resistant Staphylococcus aureus, MRSA) and a fungus (Malassezia furfur) were investigated. The antibacterial and antifungal activities were influenced by the substituents on tryptanthrin, with halogen-substituted tryptanthrin derivatives (T2Cl, T2Br, T8F, T8Br, and T2Br8Br) showing the highest potency against MRSA and M. furfur.
- 一般社団法人 日本MRSの論文
一般社団法人 日本MRS | 論文
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