Evaluation of Renal Involvement in Children with Crimean-Congo Hemorrhagic Fever
スポンサーリンク
概要
- 論文の詳細を見る
The aim of the present study was to evaluate renal involvement in children with Crimean-Congo hemorrhagic fever (CCHF). Forty-four children infected with CCHF virus and 30 controls were enrolled in the study. Urine neutrophil gelatinase-associated lipocalin (uNGAL) and urine protein levels were measured in the patient and control groups. Clinical and laboratory findings of the patient and control groups were compared. uNGAL levels were higher in the patient group than that in the control group (P < 0.001). Of the 44 patients, 26 (59.1%) were proteinuric. uNGAL levels in proteinuric patients were higher than those in non-proteinuric patients (P = 0.035). There was a positive correlation between uNGAL and urine protein levels in the patient group. (R = 0.614, P < 0.001). Due to renal involvement, increased proteinuria and increased uNGAL levels were observed in children with CCHF. In these children, measuring urine total protein and uNGAL levels can be useful to monitor renal involvement due to CCHF.
- National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committeeの論文
著者
-
Deveci Koksal
Department Of Biochemistry And Clinical Biochemistry Ataturk Training Hospital
-
Kaya Ali
Department of Pediatrics, School of Medicine, Cumhuriyet University
-
Uysal Elif
Department of Clinical Microbiology, School of Medicine, Cumhuriyet University
-
Sancakdar Enver
Department of Clinical Biochemistry, School of Medicine, Cumhuriyet University
-
Alkan Filiz
Department of Clinical Biochemistry, School of Medicine, Cumhuriyet University
-
Deveci Köksal
Department of Clinical Biochemistry, School of Medicine, Cumhuriyet University
関連論文
- Pregnancy-associated plasma protein-A and C-reactive protein levels in pre-eclamptic and normotensive pregnant women at third trimester
- Evaluation of Renal Involvement in Children with Crimean-Congo Hemorrhagic Fever