舌癌動注化学療法中に発症した一過性急性脳症の1例

概要

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We describe our experienced with a case of acute encephalopathy fugax associated with intra-arterial infusion chemotherapy for tongue cancer, which seemed to be reversible posterior leukoencephalopathy possibly related to cisplatin. A 58-year-old man was treated by intra-arterial infusion chemotherapy with cisplatin plus oral TS-1 for tongue cancer. Immediately after the 10th intra-arterial injection of cisplatin, the patient had acute encephalopathy associated with right motor paralysis of the right limbs, aphasia, disorientation, cortical blindness,and tonic convulsions. The next day, all symptoms improved. It is rare that acute encephalopathy occurs, but the risk should be considered in patients given chemotherapy.
Japanese Society of Oral and Maxillofacial Surgeonsの論文