上顎洞に進展した細胞性神経鞘腫の1例

概要

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Cellular Schwannoma is a subtype of Schwannoma, characterized by high cellularity, a largely Antoni A pattern, and absence of well-formed Verocay bodies. We report a rare case of cellular Schwannoma arising in the maxillary sinus. A 44-year-old man was referred to our hospital because of a swelling in the left buccal region. A computed tomographic scan showed a low density lesion in the left maxillary sinus. The clinical diagnosis was a maxillary tumor, and enucleation was performed. Histologically, the lesion was mainly composed of spindle cells showing high cellularity. The lesion contained hyalinization, collections of lipid-laden histiocytes, lymphocytic infiltrates, and hemosiderin deposits. Immunohistochemically, the spindle cells were strongly positive for S-100 protein and negative for GFAP, EMA, and Leu-7. Positive reactions for Ki-67 were found in the nuclei of a few tumor cells. The histopathological diagnosis was cellular Schwannoma.
Japanese Society of Oral and Maxillofacial Surgeonsの論文