Ineffectiveness of Daptomycin in the Treatment of Septic Pulmonary Emboli and Persistent Bacteremia Caused by Methicillin-resistant Staphylococcus aureus
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概要
- 論文の詳細を見る
A 73-year-old man with long-term food deprivation and total parenteral nutrition was diagnosed with septic pulmonary emboli (SPE) and a persistent bacteremia caused by central line-associated blood stream methicillin-resistant Staphylococcus aureus (MRSA) infection. Although daptomycin (DAP) failed to treat the persistent bacteremia, linezolid successfully controlled it. DAP is inactivated by lung surfactant, and therefore, it should not be administered for lower respiratory infections. However, SPE caused by MRSA has been reported to be treatable with DAP since it is an infection of the lung parenchyma. We herein report the lack of effect of daptomycin in SPE treatment.
- 社団法人 日本内科学会の論文
著者
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Hagiya Hideharu
Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
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Otsuka Fumio
Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan
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Hagioka Shingo
Emergency Unit and Critical Care Center, Tsuyama Central Hospital, Japan
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