New Treatment Strategies to Eradicate Cancer Stem Cells and Niches in Glioblastoma
スポンサーリンク
概要
- 論文の詳細を見る
Glioblastoma multiforme (GBM) harbors are not only rapidly dividing cells but also small populations of slowly dividing and dormant cells with tumorigenesity, self-renewal, and multi-lineage differentiation capabilities. Known as glioblastoma stem cells (GSCs), they are resistant to conventional chemo- and radiotherapy and may be a causative factor in recurrence. The treatment outcome in patients with GBM remains unsatisfactory and their mean survival time has not improved sufficiently. We studied clinical evidence and basic research findings to assess the possibility of new treatment strategies that target GSCs and their specific microenvironments (GBM niches) and raise the possibility of adding new treatments to eradicate GSCs and GBM niches.
- 社団法人 日本脳神経外科学会の論文
社団法人 日本脳神経外科学会 | 論文
- Long-term Outcome of Unruptured Giant Cerebral Aneurysms
- Cerebral Venous Sinus Thrombosis Associated With Iron Deficiency : Two Case Reports
- 浅側頭動脈-中大脳動脈吻合術による症候性脳血管攣縮治療の試み
- Administration of Free Radical Scavenger Edaravone Associated With Higher Frequency of Hemorrhagic Transformation in Patients With Cardiogenic Embolism
- 自家骨髄移植を併用した大量抗癌剤投与法 : 悪性脳腫瘍への応用