Recent Progress in the Understanding of Pediatric Pulmonary Hypertension and Pulmonary Vascular Disease Associated with Congenital Heart Disease: Before the 5th Pulmonary Hypertension International Symposium in Nice 2013

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概要

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• While the 5<SUP>th</SUP> pulmonary hypertension international symposium in Nice 2013 is approaching, key recent advances after the 4th international symposium in the field of pediatric pulmonary hypertension and vasculopathy related to congenital heart diseases were reviewed. Especially, meta-analysis of disease-specific compounds, epidemiology, and the genotype-phenotype correlation in adult and pediatric pulmonary arterial hypertension, recent translational research using human tissue samples and recent animal models, the impact of disease-specific compounds in Eisenmenger syndrome, and issues in Fontan circulation and hypoplastic pulmonary arteries were highlighted. Cellular molecular biology studies and clinical and population science in this field may converge via molecular genetics and studies using lung samples and new animal models to ultimately bridge the knowledge gap between them. Science in the right heart system, including pulmonary hypertension, pulmonary vasculopathy, and right heart failure, would be an evolving field of research at present and in the future.

著者

• 三谷 義英

  三重大学大学院医学研究科小児発達医学

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• Recent Progress in the Understanding of Pediatric Pulmonary Hypertension and Pulmonary Vascular Disease Associated with Congenital Heart Disease: Before the 5th Pulmonary Hypertension International Symposium in Nice 2013
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