Regulation of skeletal muscle GLUT-4 expression by exercise and nutritional stimuli

スポンサーリンク

概要

• 論文の詳細を見る

• Skeletal muscle is the primary site of glucose uptake in humans. Glucose transport activity, which is the rate-limiting step in muscle glucose metabolism, is linearly related to the content of the GLUT-4 isoform of the glucose transporter. Therefore, the level of GLUT-4 in skeletal muscle may be an important determinant of whole-body glucose disposal. It has been well documented that long-term, low- to moderate-intensity endurance exercise training induces an increase in muscle GLUT-4 content. However, emerging evidence suggests that an adaptive increase in GLUT-4 occurs even after a single acute bout of exercise or high-intensity intermittent exercise training. Recent findings also indicate that nutritional status affects GLUT-4 expression in skeletal muscle. This review provides an overview of the effects of exercise and nutritional status on GLUT-4 content in skeletal muscle, and summarizes recent progress in elucidating the molecular regulation of muscle GLUT-4 gene expression by exercise and nutritional stimuli.

著者

• Higuchi Mitsuru

  Faculty Of Sport Sciences Waseda University

• Terada Shin

  Department Of Sports Medical Science School Of Sport Sciences Waseda University

• Tabata Izumi

  Faculty Of Sport And Health Science Ritsumeikan University

• Higashida Kazuhiko

  Faculty of Sport Sciences, Waseda University

関連論文

• The Different Effects of Fluid with and without Carbohydrate Ingestion on Subjective Responses of Untrained Men during Prolonged Exercise in a Hot Environment
• Dissociation between PGC-1α and GLUT-4 Expression in Skeletal Muscle of Rats Fed a High-Fat Diet
• An Investigation of Measuring Apparatus for Vo_2 During Exercise,and Effects of 10-week Exercise Training on Aerobic Work Capacity,Body Composition and Oxidative Enzymes in Skeletal Muscle in Obese-Diabetic Model OLETF Rats
• 2E3:Effects of exercise intensity on maximum oxygen uptake(VO2max)and oxidative enzymes in skeletal muscle in OLETF rats
• Drift in Oxygen Consumption during Prolonged Sub-maximal Exercise in Subjects of Different Training Status
• 1-O-11 Mitochondrial haplogroups associated with elite Japanese athlete status(The Proceedings of the 17th Annual Meetings of Japan Society of Exercise and Sports Physiology Jury 25-26, (Tokyo))
• Relationship between Blood Adipocytokines and Resting Energy Expenditure in Young and Elderly Women
• Attenuated Increases in Blood Pressure by Dynamic Resistance Exercise in Middle-Aged Men
• Branched-Chain Amino Acid-Containing Dipeptides, Identified from Whey Protein Hydrolysates, Stimulate Glucose Uptake Rate in L6 Myotubes and Isolated Skeletal Muscles
• 1P-Y-25 Regulatory factors for postexercise glycogen resynthesis in rat skeletal muscle(The Proceedings of the 16th Annual Meetings of Japan Society of Exercise and Sports Physiology August 2-3, (Nara))
• 1P-Y-33 Potential role of lipin-1 in mitochondrial enzyme adaptation to endurance exercise in rat skeletal muscle(The Proceedings of the 16th Annual Meetings of Japan Society of Exercise and Sports Physiology August 2-3, (Nara))
• 2P-P-03 Dietary fatty acids influence mitochondrial enzyme activities and PGC-1α protein content in rat skeletal muscle(The Proceedings of the 16th Annual Meetings of Japan Society of Exercise and Sports Physiology August 2-3, (Nara))
• 2-P-33 Effect of milk intake on glycogen replenishment in rat skeletal muscle and liver(The Proceedings of the 17th Annual Meetings of Japan Society of Exercise and Sports Physiology Jury 25-26, (Tokyo))
• Effect of High-Intensity Intermittent Swimming Training on Fatty Acid Oxidation Enzyme Activity in Rat Skeletal Muscle
• EFFECTS OF CARBONATED AND NONCARBONATED BEVERAGE INTAKES IN RESPONSE TO PROLONGED CYCLE ERGOMETER EXERCISE(Proceedings of The 8^ Asian Federation of Sports Medicine Congress 2005 Tokyo)
• 123 Effect of high-intensity intermittent swimming training on fatty acid oxidation enzyme activity in rat skeletal muscle
• Effects of high-intensity intermittent swimming training on GLUT-4 content in rat skeletal muscle
• (E41007) Effect of High-intensity Intermittent Swimming Training on GLUT-4 Content in Rat Skeletal Muscle.
• Change in PGC-1α Expression in Rat Skeletal Muscle after Low-intensity Prolonged Swimming Exercise
• 2P-P-29 Effects of high-intensity intermittent training on the water for the improvement of rowing performance(The Proceedings of the 16th Annual Meetings of Japan Society of Exercise and Sports Physiology August 2-3, (Nara))
• Resting Energy Expenditure Can Be Assessed by Fat-Free Mass in Female Athletes Regardless of Body Size
• Characteristics of Body Composition and Resting Energy Expenditure in Lean Young Women
• A DIGE proteomic analysis for high-intensity exercise-trained rat skeletal muscle
• Effects of nonexhaustive bouts of high-intensity intermittent swimming training on GLUT-4 expression in rat skeletal muscle
• Effect of combined resistance and aerobic training on reactive hyperemia in men
• Association between Muscular Strength and Metabolic Risk in Japanese Women, but Not in Men
• Rowing as an aerobic and resistance exercise for elderly people
• The Effects of Sports Drink Osmolality on Fluid Intake and Immunoendocrine Responses to Cycling in Hot Conditions
• Fat-Free Mass Can Be Utilized to Assess Resting Energy Expenditure for Male Athletes of Different Body Size
• Regulation of skeletal muscle GLUT-4 expression by exercise and nutritional stimuli
• Relative Contribution of Organs Other Than Brain to Resting Energy Expenditure Is Consistent among Male Power Athletes
• Effect of long-term voluntary exercise and energy restriction on bone mineral density in mature female rats
• Dietary Reference Intakes for Japanese 2010: Energy
• Reference Values for Cardiorespiratory Fitness and Incidence of Type 2 Diabetes

もっと見る 閉じる

スポンサーリンク