Immunohistochemical Distribution of Protozoa in Experimental Porcine Toxoplasmosis

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概要

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• In this study, we investigated the distribution of lesions and protozoa in LWD piglets inoculated orally with oocysts of <I>Toxoplasma gondii </I>(Strain O-1) isolated from a cat. Infected piglets developed fever, diarrhea, dyspnea and loss of appetite. They were euthanatized at 8 and 10 days after the inoculation. Histologically, necrotic and nonsuppurative inflammatory lesions were observed in many different organs, more severely in the lymph nodes, thymus, spleen, stomach, intestine, adrenal gland, pancreas, lungs and liver. Minor lesions were observed in the bone marrow, tongue, heart, skeletal muscles, spinal cord and brain. Using an immunohistochemical staining technique, we were able to confirm the presence of tachyzoites in all of the above-mentioned organs as well as some other organs that were characterized by an absence of necrotic lesions such as the salivary glands and kidney.

• 独立行政法人　国際農林水産業研究センターの論文

著者

• YAMADA Manabu

  Laboratory of Animal Physiology, School of Bioresources, Hiroshima Prefectural University

• YAMADA Manabu

  Laboratory of Chronic Disease Pathology, National Institute of Animal Health

• BAÑALES Pedro

  DI. LA. VE., Department of Pathobiology/Reproduction

• NARITA Minoru

  Laboratory of Chronic Disease Pathology, National Institute of Animal Health

• SHIMURA Kameo

  Laboratory of Chronic Disease Pathology, National Institute of Animal Health

• NAKAMURA Kikuyasu

  Laboratory of Chronic Disease Pathology, National Institute of Animal Health

関連論文

• Isolation and Partial Characterization of a Bovine Amniotic Fluid Protein
• Immunohistochemical Distribution of Protozoa in Experimental Porcine Toxoplasmosis

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