The study of acute exacerbation of sinus symptoms in eosinophilic sinusitis

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This study involved 21 patients who were treated for eosinophilic sinusitis from July 2009 to June 2010 at the Department of Otorhinolaryngology, Japanese Red Cross Medical Center. We investigated the causes, treatment approaches, and outcomes of acute exacerbation of sinus symptoms, such as impaired sense of smell, rhinorrhea, and nasal obstruction. The relationship between seasonal factors and acute exacerbation of sinusitis were also assessed. Eleven of the 21 patients with eosinophilic sinusitis had a total of 23 episodes of acute exacerbation. The most frequent symptom was impaired sense of smell (22 episodes), followed by exacerbated rhinorrhea (14 episodes) and nasal obstruction (12 episoeds). Sinus symptoms improved in 19 of the 23 episodes for a fair outcome. Although acute exacerbation was most frequently caused by cold and asthma, it also resulted from temporary discontinuation of steroid therapy, such as oral steroid administration or betametasone nasal drops, for the prevention of adverse effects. Acute exacerbation of eosinophilic sinusitis was distributed almost throughout the year, with the highest frequency seen at the change of the seasons, such as in March and June. The survey results showed that sinus symptoms are generally exacerbated during winter through early spring when cold, asthma, and hay fever are prevalent.