繊毛虫の生命現象を司る鍵物質

概要

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Protozoan ciliates are eukaryotic unicellular organisms characterized by the presence of hair-like organelles called cilia. In this article the chemistries of biologically active natural products, especially focused on and also the toxic chemicals which function as defense substances against the predators the compounds leading to conjugation of the cells, are described. Isolation and the synthesis of the colorless defense toxins spirostomin from Spirostomum teres and climacostol from Climacostomum virensare also described.Enantiomerically pure blepharismone (also named gamone 2), a mating inducing pheromone produced by type II cells of the ciliate Blepharisma japonicum were practically synthesized via Stille cross-coupling reaction.