Tubulointerstitial Nephritis and Primary Biliary Cirrhosis with a T Cell-dominant Profile of Infiltrating Cells and Granulomas in Both Organs
スポンサーリンク
概要
- 論文の詳細を見る
A 46-year-old woman was admitted to our hospital for an evaluation of progressive renal insufficiency and elevated liver enzymes. A renal biopsy revealed chronic granulomatous interstitial nephritis. Her laboratory findings indicated primary biliary cirrhosis (PBC), which was confirmed with a liver biopsy. CD4+ T cells and CD8+ T cells with granuloma formation were the predominant cells infiltrating into the interstitium of the kidneys and liver. The etiology of tubulointerstitial nephritis in the present patient was not clear; however, it might have shared the same pathogenesis as PBC due to the relatively close onset, the similar profiles of infiltrating cells and the presence of granulomas.
著者
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Baba Satoshi
Department Of Cardiology Kishiwada City Hospital
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Kato Akihiko
Blood Purification Unit Hamamatsu University School Of Medicine
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Yasuda Hideo
Internal Medicine I, Division of Nephrology, Hamamatsu University School of Medicine, Japan
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Ohashi Naro
Internal Medicine I, Division of Nephrology, Hamamatsu University School of Medicine, Japan
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Kato Akihiko
Blood Purification Unit, Hamamatsu University School of Medicine, Japan
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Iwakura Takamasa
Internal Medicine I, Division of Nephrology, Hamamatsu University School of Medicine, Japan
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Fujigaki Yoshihide
Internal Medicine I, Division of Nephrology, Hamamatsu University School of Medicine, Japan
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Matsuyama Takashi
Internal Medicine I, Division of Nephrology, Hamamatsu University School of Medicine, Japan
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Fujikura Tomoyuki
Internal Medicine I, Division of Nephrology, Hamamatsu University School of Medicine, Japan
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