Pneumonitis Induced by Rifampicin: A Case Report and Literature Review

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概要

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• An 84-year-old woman being treated for miliary tuberculosis (TB) with rifampicin (RFP), isoniazid (INH), ethambutol (EB) and corticosteroids suffered from a persistent fever for five months. While tapering the dose of prednisolone, chest computed tomography (CT) revealed diffuse ground glass opacities (GGO) and bronchoalveolar lavage fluid (BALF) showed an increase in lymphocytes. After the anti-TB drugs were discontinued and the dose of the corticosteroids was increased, the CT findings and fever improved considerably. However, readministration of RFP provoked an inflammatory reaction, leading to a diagnosis of RFP-induced pneumonitis. This condition is very rare. This is the first report of RFP-induced pneumonitis occurring during adjunct steroid therapy.

著者

• Kimura Kengo

  Respiratory Center, Shinko Hospital, Japan

• Koma Yasuko

  Respiratory Center, Shinko Hospital, Japan

• Goto Keiko

  Respiratory Center, Shinko Hospital, Japan

• Yoshida Chihiro

  Respiratory Center, Shinko Hospital, Japan

• Matsumoto Yusuke

  Respiratory Center, Shinko Hospital, Japan

• Koyama Midori

  Respiratory Center, Shinko Hospital, Japan

• Nakashima Nariyasu

  Respiratory Center, Shinko Hospital, Japan

• Masuya Daiki

  Respiratory Center, Shinko Hospital, Japan

• Matsuoka Hirofumi

  Respiratory Center, Shinko Hospital, Japan

• Yoshimatsu Harukazu

  Respiratory Center, Shinko Hospital, Japan

• Suzuki Yujiro

  Respiratory Center, Shinko Hospital, Japan

関連論文

• Pneumonitis Induced by Rifampicin: A Case Report and Literature Review

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