Pulmonary Tumor Thrombotic Microangiopathy with Circulatory Failure Treated with Imatinib
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概要
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Pulmonary tumor thrombotic microangiopathy is a lethal, yet difficult to diagnose, complication of gastrointestinal carcinoma. Even if properly diagnosed, there is no treatment, especially after a circulatory collapse. We herein report a case of pulmonary tumor thrombotic microangiopathy with circulatory failure due to pulmonary hypertension. The patient was temporarily successfully treated with imatinib, an inhibitor of the platelet-derived growth factor receptor. Pulmonary hypertension was dramatically ameliorated and the patient was able to be weaned from percutaneous cardiopulmonary support within 20 days of treatment. Imatinib may be effective for ameliorating pulmonary hypertension that is caused by pulmonary tumor thrombotic microangiopathy.
- 社団法人 日本内科学会の論文
著者
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Ogawa Aiko
Department Of Cardiovascular Medicine Okayama University Graduate School Of Medicine And Dentistry
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Matsubara Hiromi
Department Of Bioscience Department Of Cardiovascular Surgery
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Matsubara Osamu
Department Of Basic Pathology National Defense Medical Collage
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Yamadori Ichiro
Department Of Clinical Pathology National Hospital Organization Okayama Medical Center
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Ogawa Aiko
Department of Clinical Science, National Hospital Organization Okayama Medical Center, Japan
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YAMADORI Ichiro
Department of Clinical Laboratory Medicine, National Hospital Organization Okayama Medical Center
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