Traffic Flow and Translation Process

スポンサーリンク

概要

• 論文の詳細を見る

• Messenger RNAs (mRNA), that code sequences of amino acids by using triplets of nucleotides (codons), are translated by multiple ribosomes. Usually more than one codon corresponds to an amino acid. The ribosome speed is known to dependent on the codon, thus there is a room to keep an amino acid sequence (protein) and change the ribosome speed. We model the ribosome traffic with codon-dependent rate estimated for E. coli and show that some wild type codon sequences can regulate "traffic jam" by placing slow codons at the begging of the mRNA. We discuss possible roles of slow codons in translation process.

• 日本生物物理学会の論文

著者

• 御手洗 菜美子

  コペンハーゲン大学ニールス・ボーア研究所

関連論文

• Traffic Flow and Translation Process

スポンサーリンク