Styrene Altered Clock Gene Expression in Serum-Shocked Cultured Human Fibroblasts
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概要
- 論文の詳細を見る
The circadian clock can regulate the metabolic process of xenobiotics, but little is known as to circadian rhythms can be perturbed by xenobiotics. Styrene is a organic chemical widely used in occupational settings. The effects of styrene on the circadian genes of HuDE cells were evaluated after serum-shocking synchronization. A subtoxic dose of 100 µM of styrene altered the expression of clock genes BMAL1, PER2, PER3, CRY1, CRY2, and REV-ERB-α.
- 公益社団法人 日本農芸化学会の論文
著者
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Santarelli Lory
Department Of Molecular Pathology And Innovative Therapies Clinic Of Occupational Medicine Polytechn
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Amati Monica
Department Of Molecular Pathology And Innovative Therapies Clinic Of Occupational Medicine Polytechn
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BRACCI Massimo
Department of Clinical and Molecular Sciences, Polytechnic University of Marche
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MANZELLA Nicola
Department of Clinical and Molecular Sciences, Polytechnic University of Marche
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STAFFOLANI Sara
Department of Clinical and Molecular Sciences, Polytechnic University of Marche
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STRAFELLA Elisabetta
Department of Clinical and Molecular Sciences, Polytechnic University of Marche
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RAPISARDA Venerando
Department of Internal Medicine and Systemic Diseases, University of Catania
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VALENTINO Matteo
Department of Clinical and Molecular Sciences, Polytechnic University of Marche
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COPERTARO Alfredo
ASUR Area 2, Loreto Hospital
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SANTARELLI Lory
Department of Clinical and Molecular Sciences, Polytechnic University of Marche
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AMATI Monica
Department of Clinical and Molecular Sciences, Polytechnic University of Marche
関連論文
- Relationship of Job Satisfaction, Psychological Distress and Stress-Related Biological Parameters among Healthy Nurses : A Longitudinal Study
- Styrene Altered Clock Gene Expression in Serum-Shocked Cultured Human Fibroblasts