Study of Exclusion Criteria for Reference Intervals of Cholesterol, Triglyceride and HDL-cholesterol
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We studied exclusion criteria to determine the reference intervals for cholesterol (TCHO), triglyceride (TG), and HDL-cholesterol (HDLC) according to the NCCLS-proposed guideline. Significance of differences on lipid tests was examined between healthy subjects and subjects with few symptoms. Ranking of the usefulness of 35 laboratory tests on TCHO, TG, HDLC tests was calculated using multiple regression analysis in a single operation. Hypertension, hyperlipemia, hyperuricemia, diabetes, and liver diseases were found to affect the data of TCHO, TG and HDLC, respectively. Data for the lipid tests were also highly correlated with the those of lactate dehydrogenase, cholinesterase, uric acid, glucose and body mass index which reflect the nutritional conditions. The reference intervals obtained from this study were wider than the therapeutic management decision levels recommended by the Japan atherosclerosis society.
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- Study of Exclusion Criteria for Reference Intervals of Cholesterol, Triglyceride and HDL-cholesterol