Studies on energy metabolism in the brain:I. Adenylate energy charge in the brain under the condition of anoxia
スポンサーリンク
概要
- 論文の詳細を見る
Concentrations of adenine nucleotides in rat brain and liver have been determined spectrofluorometrically by the coupled enzymatic reactions and the value of energy charge ([ATP]+0.5[ADP]/[ATP]+[ADP]+[AMP]) has been calculatated. The value of energy charge of normal rat brain and liver was 0.89 and 0.85, respectively.<BR>When rat was inhaled with 100% nitrogen gas, the value of energy charge of the brain decreased rapidly to 0.48 at 2 min after the inhalation. This was due to a rapid decrease in ATP concentration in the brain and a concomitant increase in AMP concentration. On the other hand, that of the liver was reduced slowly to 0.69 at 2 min under the same conditions.<BR>The results indicate clearly a higher affinity of the brain tissue to oxygen than the liver.
- Japan Society of Clinical Chemistryの論文
著者
関連論文
- 486 肝冷却保存中及び再潅流後の内在性抗酸化物質の変動 : UW液の有効性について(第38回日本消化器外科学会総会)
- コエンザイムQの抗酸化作用
- 細胞質アデニル酸キナーゼによるチアミン三リン酸生合成
- 308 小腸移植の展望 : 特に小腸保存後の再灌流障害について(第40回日本消化器外科学会総会)
- 小腸におけるアミノ酸輸送とその調節
- 肝細胞膜インスリンレセプターに関する基礎的研究
- Studies on energy metabolism in the brain:I. Adenylate energy charge in the brain under the condition of anoxia
- Alteration in Serum Myoglobin Level as Diagnostic Significance in Myocardial Infarction