Acceleration of Aniline Hydroxylation by Human Red Cells Due to the Presence of Methylene Blue

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概要

• 論文の詳細を見る

• Aniline hydroxylation by human red cells was studied in the absence or presence of methylene blue. In the presence of methylene blue, aniline hydroxylation by human red cells was considerably accelerated. The effect of monoiodo acetate, removal of glucose, cyanide, aminotriazol and atebrin on the rate of aniline hydroxylation was also studied in the presence of methylene blue. On the basis of these results, the mechanism of acceleration of aniline hydroxylation by human red cells in the presence of methylene blue was discussed in relation to NADPH electron flow system in the red cells. The aniline hydroxylating activity of whole red cells in the body was shown to be comparable to that of one liver when methylene blue was given.

• Japan Society of Clinical Chemistryの論文

著者

• 米山 良昌

  金沢大学医学部生化学教室

• 竹下 正純

  金沢大学医療短期大学部生化学

• 竹下 正純

  金沢大学医学部生化学

• 友田 煙夫

  金沢大学医学部生化学

• 指吸 俊次

  金沢大学医学部生化学

• 米山 良昌

  金沢大学医学部生化学

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