IMPROVEMENTS IN OXYGEN TRANSFER IN A LIQUID-LIQUID MEMBRANE OXYGENATOR USING PERFLUOROOCTYLBROMIDE

概要

論文の詳細を見る
When a membrane oxygenator is used in a liquid-liquid system, entrainment of oxygen bubbles and cell damage caused by the direct contact with the bubbles are eliminated. Enhancement of oxygen transfer rate may give high performance to the membrane oxygenator with high safety. Oxygen transfer experiments were made to determine the oxygen transfer rate of a dialyzer (S. SP-1.5H:Senko Medical Instrument Mfg.) composed of Cuprophan membrane used as a membrane oxygenator. Water, stroma free hemoglobin (SFH) and perfluorooctyl-bromide (PFOB) for gas carriers were used to transfer enough oxygen to water and bovine blood. When PFOB was caused to flow inside the hollow and then the blood outside, oxygen transfer rate was ade-quate. No leak of hydrophobic PFOB to the blood was further observed using hydrophilic membranes.
一般社団法人日本人工臓器学会の論文