Studies on expanded polytetrafluoroethylene as the vascular prosthesis (the third report)

概要

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Our comparative studies of fluorinated materials which was used as the vascular prostheses for large caliber veins disclosed that surface properties and porosity highly corresponded with the thickness of the layer of thrombus in the inner surface. In the nonoporous prostheses (polytetrafluoroethylene-hexafluoropropylene, polytetrafluoroethylene-hexafluoropropylene-methylmetacryate.) initial platelet adhesion was seen from 24 hours to 120 hours after insertion into superior vena cava and inferior vena cava, and thrombus formation was seen in only one case during this period. In expanded poly-tetrafluoroethylene prostheses of 2-4 microns pore size, thin layer of thrombus which might be changed into the neointima was seen. On the other hand in ex-panded polytetrafluoroethylene prostheses of 7-10 microns pore size, thick layer of thrombus which could be enough to occlude the lumen was seen.
一般社団法人日本人工臓器学会の論文