The Evaluation What Cause Heart Failure in the Patient Has Paroxysmal Atrial Fibrillation with Preserved Systolic Function

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Background: Atrial fibrillation (AF) sometimes cause heart failure (HF) even if a patient has preserved left ventricular (LV) systolic function, but there is unclear what factor lead to heart failure. Methods and Results: From 2008 Sep to 2010 Sep, 180 patients with AF divide decompensate group (DECO, n=33) is led into NYHA III or IV HF and not decompensate group (NOR, n=147) is otherwise. We exclude under ejection fraction (EF) 55%, adaptation of valvular disease. Data are described consecutively DECO and NOR. Age is 75.3±9.5, 65.1±12.6 (p<0.0001). Male gender is 45.5% and 71.4% (p=0.004). Hypertension is 93.9%, 59.9% (p=0.0002). Hypertrophic cardiomyopathy is 33.3% and 12.9% (p=0.0045). Ischemic heart disease is 21.2% and 6.8% (p=0.01). Chronic kidney disease is 21.2% and 8.2% (p=0.028). Left atrial diameter is 43.3±7.9 mm and 39.1±6.0 mm (p=0.0008). The e′ is 5.1±1.6 cm/s and 7.2±2.1 cm/s (p<0.0001). E/e′ is 19.0±12.0 and 11.2±4.5 (p<0.0001). Heart rate on attack is 136±20 bpm and 121±37 bpm (p=0.052). Diabetes mellitus, stroke, valvular disease, medications, LV diastolic diameter, LV systolic diameter, EF, and E/A have no significant difference. Multivariable logistic regression analysis shows that E/e′ and age have relative risks 1.138 (95%CI, 1.026–1.261) and 1.069 (95%CI, 1.008–1.133), respectively. Conclusion: E/e′ and age are independent predictors of HF when patient fall into paroxysmal AF with preserved systolic function.

The Evaluation What Cause Heart Failure in the Patient Has Paroxysmal Atrial Fibrillation with Preserved Systolic Function

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