Impact of Total Area of Left Atrial Complex Fractionated Electrograms on Catheter Ablation of Atrial Fibrillation
スポンサーリンク
概要
- 論文の詳細を見る
<B>Background:</B> It was reported that ablation of complex fractionated atrial electrograms (CFAE) added to pulmonary vein isolation (PVI) was effective in some patients with atrial fibrillation (AF). However, it has been unclear the impact of total area of CFAE on catheter ablation in these patients. <B>Methods:</B> Consecutive 29 patients (paroxysmal (PAF): n=17, persistent (PerAF): n=12) who underwent catheter ablation of AF were studied. Left atrial mapping was performed by electroanatomical mapping system during ongoing AF. 98±15 points per patients were determined to CFAE by automated software. The points with an Average Complex Interval (ACI) <75 ms were considered as highly frequent CFAE (HF-CFAE). Total area of HF-CFAE was measured in the LA. After the mapping, PVI was performed in all the patients, except one patient who developed cardiac tamponade during the mapping. Additional ablation was performed if AF was not terminated after PVI. <B>Results:</B> Total area of HF-CFAE was significantly smaller in PAF than PerAF (18.1±8.5 cm<SUP>2</SUP> versus 44.2±31.5 cm<SUP>2</SUP>, p=0.003). AF termination was observed more frequently in PAF (93.7% vesus 33.5%, p=0.0007). There was significant difference of HF-CFAE area between patients with AF termination by catheter ablation and patients who required electrical cardioversion (20.8±11.29 cm<SUP>2</SUP> versus 47.8±35.0 cm<SUP>2</SUP>, p=0.0047). <B>Conclusions:</B> PerAF had significantly larger HF-CFAE area than PAF. AF termination by catheter ablation was associated with total area of HF-CFAE in the LA.
著者
-
YAMASHITA Takeshi
The Cardiovascular Institute
-
SAGARA Koichi
The Cardiovascular Institute
-
OTSUKA Takayuki
The Cardiovascular Institute
関連論文
- Recruitment of Immune Cells Across Atrial Endocardium in Human Atrial Fibrillation
- Infiltration of Macrophages Through the Atrial Endocardium of Inflammation-Induced Rats : Contribution of Fractalkine
- PJ-565 Aging-related Regional Inhomogeneities in Macrophage Infiltration and Interstitial Fibrosis in Rat Atria(PJ095,Arrhythmia, Others (Basic) 2 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-435 Promotion of Macrophage Infiltration and Interstitial Fibrosis in Diabetic Rat Atria(PJ073,Arrhythmia, Others (Basic) 1 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Comparison of Antiarrhythmics Used in Patients With Paroxysmal Atrial Fibrillation : Subanalysis of J-RHYTHM Study
- PJ-321 The Relationships between Urinary Albumin and Prevalence of Cardiac Diseases in Japanese Patients(PJ054,Kidney/Renal Circulation/CKD 3 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PE-536 The Relationships between BNP and AF in Japanese Patients(PE090,Heart Failure (Biomarker) 2 (M),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)
- OE-354 Mortality of Japanese AF Patients According to CHADS2 Score, Its Components, and Other Comorbidities : From Shinken Database 2004-7(OE60,Atrial Fibrillation/Supraventricular Arrhythmia: Epidemiology and Pathophysiology (A),Oral Presentation (Englis
- OE-352 Comparison of Age-dependent Mortality between AF Patients and General Population in Japan(OE60,Atrial Fibrillation/Supraventricular Arrhythmia: Epidemiology and Pathophysiology (A),Oral Presentation (English),The 73rd Annual Scientific Meeting of T
- OE-218 The Relationships between Urinary Albumin and Prevalence of AF in Japanese Patients(OE37,Kidney/Renal Circulation/CKD 1 (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Optimal Treatment Strategy for Patients With Paroxysmal Atrial Fibrillation : J-RHYTHM Study(Arrhythmia/Electrophysiology)
- 5 Randomized Controlled Trial of Rhythm vs Rate Control Strategy in Japanese Patients with Paroxysmal and Persistent Atrial Fibrillation (J-RHYTHM Study)(Late Breaking Clinical Trials in Japan, The 71st Annual Scientific Meeting of the Japanese Circulatio
- Randomized Study of Angiotensin II Type 1 Receptor Blocker vs Dihydropiridine Calcium Antagonist for the Treatment of Paroxysmal Atrial Fibrillation in Patients With Hypertension : The J-RHYTHM II Study Design for the Investigation of Upstream Therapy for
- Investigation of the Optimal Treatment Strategy for Atrial Fibrillation in Japan : The J-RHYTHM (Japanese Rhythm Management Trial for Atrial Fibrillation) Study Design
- OE-354 Mortality of Japanese AF Patients According to CHADS2 Score, Its Components, and Other Comorbidities : From Shinken Database 2004-7(OE60,Atrial Fibrillation/Supraventricular Arrhythmia: Epidemiology and Pathophysiology (A),Oral Presentation (Englis
- OE-352 Comparison of Age-dependent Mortality between AF Patients and General Population in Japan(OE60,Atrial Fibrillation/Supraventricular Arrhythmia: Epidemiology and Pathophysiology (A),Oral Presentation (English),The 73rd Annual Scientific Meeting of T
- 5 Randomized Controlled Trial of Rhythm vs Rate Control Strategy in Japanese Patients with Paroxysmal and Persistent Atrial Fibrillation (J-RHYTHM Study)(Late Breaking Clinical Trials in Japan, The 71st Annual Scientific Meeting of the Japanese Circulatio
- Body Size and Atrial Fibrillation in Japanese Outpatients
- PJ-691 Role of Low EF in Prognosis of Japanese Patients with Ventricular Tachycardia : Comparison with Preserved EF(PJ116,Ventricular Arrhythmia (Clinical/Pathophysiology) (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Ci
- PJ-147 The Role of Atrial Fibrillation in Prognosis in Japanese Patients with Acute Coronary Syndrome(PJ025,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 2 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation So
- PJ-077 Association between Left Atrial Dimension and Prognosis in Japanese Patients with Cardiovascular Diseases(PJ013,Cardiac Function (Clinical) 1 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OE-354 Mortality of Japanese AF Patients According to CHADS2 Score, Its Components, and Other Comorbidities : From Shinken Database 2004-7(OE60,Atrial Fibrillation/Supraventricular Arrhythmia: Epidemiology and Pathophysiology (A),Oral Presentation (Englis
- OE-352 Comparison of Age-dependent Mortality between AF Patients and General Population in Japan(OE60,Atrial Fibrillation/Supraventricular Arrhythmia: Epidemiology and Pathophysiology (A),Oral Presentation (English),The 73rd Annual Scientific Meeting of T
- OE-354 Mortality of Japanese AF Patients According to CHADS2 Score, Its Components, and Other Comorbidities : From Shinken Database 2004-7(OE60,Atrial Fibrillation/Supraventricular Arrhythmia: Epidemiology and Pathophysiology (A),Oral Presentation (Englis
- OE-352 Comparison of Age-dependent Mortality between AF Patients and General Population in Japan(OE60,Atrial Fibrillation/Supraventricular Arrhythmia: Epidemiology and Pathophysiology (A),Oral Presentation (English),The 73rd Annual Scientific Meeting of T
- 5 Randomized Controlled Trial of Rhythm vs Rate Control Strategy in Japanese Patients with Paroxysmal and Persistent Atrial Fibrillation (J-RHYTHM Study)(Late Breaking Clinical Trials in Japan, The 71st Annual Scientific Meeting of the Japanese Circulatio
- Prevalence and Prognosis of Patients With Heart Failure in Tokyo : A Prospective Cohort of Shinken Database 2004-5
- Rate Control and Quality of Life in Patients With Permanent Atrial Fibrillation : The Quality Of Life and Atrial Fibrillation (QOLAF) Study
- Impact of reduced renal function on prognosis in Japanese patients with coronary artery disease : a prospective cohort of Shinken Database 2007
- PJ-564 Distribution of Collagen, Macrophages and Fibroblasts in Human Atria with Atrial Fibrillation(PJ095,Arrhythmia, Others (Basic) 2 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OE-426 Macrophage Infiltration in Atria Precede the Development of Arrhythmogenic Substrates of Atrial Tachyarrhythmia in Spontaneously Hypertensive Rats(OE72,Arrhythmia, Mechanism (A),Oral Presentation (English),The 73rd Annual Scientific Meeting of The
- Impact of Drug Alteration to Maintain Rhythm Control in Paroxysmal Atrial Fibrillation : Subanalysis From J-RHYTHM Study
- OE-354 Mortality of Japanese AF Patients According to CHADS2 Score, Its Components, and Other Comorbidities : From Shinken Database 2004-7(OE60,Atrial Fibrillation/Supraventricular Arrhythmia: Epidemiology and Pathophysiology (A),Oral Presentation (Englis
- PJ-018 Innate and Adaptive Immune Reactions during Progression of Atrial Fibrillation in Humans(Arrhythmia, basic(04)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-017 Recruitment of Immune Cells across Atrial Endocardium during Progression of Atrial Fibrillation in Humans: Evidence for Local Immunologic Mechanisms(Arrhythmia, basic(04)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanes
- PJ-016 Multiple Cytokines Expression in Human Atria Obtained from Cardiac Surgery(Arrhythmia, basic(04)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PE-008 Infiltration of Macrophages through Atrial Endocardium by Upregulation of Fractalkine Expression in Inflammation-induced Rats.(Arrhythmia, basic(03)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PE-007 Accumulation of Advanced Glycation End Products in Human Fibrillated Atria(Arrhythmia, basic(03)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OE-148 Involvement of SPARC Protein Expression in Interstitial Fibrosis in Human Fibrillated Atria(Arrhythmia, basic(01)(A),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OE-366 Predictors of Sinus Node Dysfunction by Modified Maze Procedure for Chronic Atrial Fibrillation in Patients Undergoing Concomitant Valvular Surgery(Valvular heart disease/Pericarditis/Cardiac tumor-1, The 71st Annual Scientific Meeting of the Japan
- OE-426 Macrophage Infiltration in Atria Precede the Development of Arrhythmogenic Substrates of Atrial Tachyarrhythmia in Spontaneously Hypertensive Rats(OE72,Arrhythmia, Mechanism (A),Oral Presentation (English),The 73rd Annual Scientific Meeting of The
- PJ-017 Recruitment of Immune Cells across Atrial Endocardium during Progression of Atrial Fibrillation in Humans: Evidence for Local Immunologic Mechanisms(Arrhythmia, basic(04)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanes
- OE-366 Predictors of Sinus Node Dysfunction by Modified Maze Procedure for Chronic Atrial Fibrillation in Patients Undergoing Concomitant Valvular Surgery(Valvular heart disease/Pericarditis/Cardiac tumor-1, The 71st Annual Scientific Meeting of the Japan
- PJ-605 The Latest Clinical Outcomes of Massive Pulmonary Embolism in the Tokyo CCU Network(PJ102,Pulmonary Circulation 2 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PE-440 The Incidence of Perioperative Complete Atrioventricular Block Associated with Percutaneous Transluminal Septal Myocardial Ablation and the Indication of Permanent Pacemaker(PE074,Cardiomyopathy/Hypertrophy (Clinical) 2 (M),Poster Session (English)
- DPJ-045 Lack of Association Large Angiographic Late Loss and Low Risk of In-Stent Thrombus : Angioscopic Comparison between Paclitaxel- and Sirolimus-Eluting Stent(DPJ08,Intravascular Imagings (I),Digital Poster Session (Japanese),The 73rd Annual Scientif
- Dose-Response Effects of Bepridil in Patients With Persistent Atrial Fibrillation Monitored With Transtelephonic Electrocardiograms : A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study (J-BAF Study)
- J Wave and ST Segment Elevation in the Inferior Leads : A Latent Type of Variant Brugada Syndrome ?
- -0112-POSTOPERATIVE RESULTS OF PATIENTS WITH DIVISION OF ACCESSORY PATHWAY FOR WPW SYNDROME
- -246- ELECTROCARDIOGRAPHIC CHANGES AND HEMODYNAMIC RESULTS FOLLOWING ENDOCARDIAL RESECTION FOR ISCHEMIC VENTRICULAR TACHYCARDIA : PTCA, CABG : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- PJ-423 Analysis of Risk Factors for Aspirin-Induced Gastrointestinal Mucosal injury in Patients with Cardiovascular Disease(Cardiovascular pharmacology, basic/clinical(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circ
- PE-476 Increased Peripheral Blood Mononuclear Cell Count is an Independent Predictor for Cardiac Events in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical(diagnosis/treatment)(07)(IHD),Poster Session(English),The 72nd Annua
- OE-274 Long-term QOL after PTSMA in symptomatic HOCM Comparing with Mild Grade Patients : Importance of preventing Sudden Death in All Cases(Cardiomyopathy, basic/clinical(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanes
- Pilsicainide-Induced Coronary Vasospasm in a Patient With Brugada-Type Electrocardiogram : A Case Report
- Effects of muscle potential depression and muscle stimulation caused by different insulation coating configurations on cardiac pacemakers
- "Hexatuple" Coronary Bypass With in Situ Arterial Grafts
- The Clinical Significance of Performing Preoperative Angiography of the Internal Thoracic Artery in Coronary Artery Bypass Surgery
- OE-227 Diabetes Mellitus Impairs Endocardial Function in Rat Atria(Thromboembolism/Antithrombotic therapy/Thrombolysis-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- A Prospective Study on the Risk-Stratification for Patients With Non-Sustained Ventricular Tachycardia Using a Novel Algorithm
- PE-019 Long-term Treatment with Olmesartan Reduced Aging-Related Interstitial Fibrosis of Rat Atria Inhomogeneously(Arrhythmia, basic-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-273 Lipopolysaccharide Induces the Down-regulation of L-type Ca^ Channel Genes in Rat Atria(Arrhythmia, basic-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- 3 Impact of the Prevention of Contrast-induced Nephropathy on Clinical Outcome and Cost-effectiveness in Pre-dialysis Patients Undergoing Coronary Intervention(Economic Aspects of Cardiovascular Catheter Intervention,Symposium 17 (SY-17) (I),The 73rd Annu
- PJ-084 Predictors and Role of RAS Inhibition in New Onset of Atrial Fibrillation : A 5-year Follow-up Study(ECG/Body surface potential mapping/Holter-6, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Critical Level of Cerebral Oxygenation During Exercise in Patients With Left Ventricular Dysfunction
- Critical Level of Cerebral Oxygenation during Exercise in Patients with Dilated Cardiomyopathy(Cerebrovascular Circulation/Stroke 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PE-327 Arrhythmogenic Substrates of Atrial Fibrillation in Hypertension(Arrhythmia, basic-4 (A) PE55,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-142 Rigid Restriction of Contrast Media during Coronary Intervention Potentially Reduces the Risk of Contrast-Induced Nephropathy in Patients with Renal Insufficiency(Coronary revascularization, PCI-07, The 71st Annual Scientific Meeting of the Japanes
- FRS-045 Favorable Occurrence of Procedure Related PTSMA Complication in Consecutive 100 Cases : NMS Single Center Experience(Therapeutic Strategies for Cardiovascular Disease, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Molecular basis for paroxysmal atrial fibrillation
- PJ-199 Clinical Parameters Determining Paroxysmal and Chronic Form of Atrial Fibrillation : From a Prospective Cohort Study of Shinken Database 2004(Arrhythmia, diagnosis/pathophysiology/EPS-12, The 71st Annual Scientific Meeting of the Japanese Circulati
- PE-127 Relationships between Sex Hormones and Atrial Fibrillation : Protective Effects of Testosterone(Arrhythmia, basic-3 (A) PE22,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-035 Olmesartan Prevents Atrial Endocardial Remodeling Induced by Atrial Fibrillation : Involvement of Angiotensin-II(Arrhythmia, basic-2 (A) OJ6,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Soc
- Nifekalant Hydrochloride, a Novel Class III Antiarrhythmic Agent, Suppressed Postoperative Recurrent Ventricular Tachycardia in a Patient Undergoing Coronary Artery Bypass Grafting and the Dor Approach
- PE-448 Evidence for the causative role of oxidative stress in the development of contrast-induced nephropathy in patients with chronic kidney disease.(Kidney/Renal circulation(04)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japane
- PE-224 Possible Role of Reactive Oxygen Species during the Development of Ischemic Preconditioning in Patients Undergoing Percutaneous Coronary Intervention.(Myocardial ischemia/reperfusion, basic/clinical(03)(IHD),Poster Session(English),The 72nd Annual
- PE-429 Heart Failure with Preserved versus Reduced Left Ventricular Systolic Function : A Prospective Hospital Cohort Study of Shinken Database 2004-5(Heart failure, clinical(11)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanes
- OE-213 Mortality and Morbidity of Japanese Patients with Heart Failure : A Prospective Hospital Cohort Study of Shinken Database 2004-5(Heart failure, clinical(03)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulatio
- FRS-027 Why Is Hypertension a Risk Factor for Thromboembolism in Atrial Fibrillation? : Demonstration of Atrial Endocardial Dysfunction in SHR Rats(Arrhythmia-Basic : Molecular and Genetic : Basis (A) : FRS4)(Featured Research Session (English))
- OE-100 Protein Therapy Using Control-Released b-FGF in Patients with Ischemic Limbs : a Possible Alternative to Bone Marrow Mononuclear Cell Implantation(Regeneration (angiogenesis/myocardial regeneration)-1, The 71st Annual Scientific Meeting of the Japa
- PE-006 Fractalkine Expression and Macrophage Infiltration in rat atria(Arrhythmia, basic(03)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- FRS-075 AGEs-RAGE System Mediates Atrial Structural Remodeling via Upregulating Connective Tissue Growth Factor in Diabetic Rat(Arrhythmia (basic), The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Molecular and Electrophysiological Differences in the L-Type Ca^ Channel of the Atrium and Ventricle of Rat Hearts(EXPERIMENTAL INVESTIGATION)
- The prognostic significance of the ventricular response during paroxysmal atrial fibrillation
- Rapid atrial stimulation acutely downregulates the expression of L-type Ca^ channel auxiliary subunit (α2δ2) in the rat atrium
- α2δ2 is an atrial-specific subunit of L-type Ca^ channel in rat hearts
- Adrenergic stimulation immediately modifies the Ca^ channel gene expression preferentially in the atrium
- Incidence of Major Bleeding Complication of Warfarin Therapy in Japanese Patients With Atrial Fibrillation
- FRS-070 Efficacy of "Early" Class III Drug AVE0118 on Alcohol-related Atrial Tachyarrhythmias(Clinical Arrhythmia-1 (A) FRS14,Featured Research Session,The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Premature Atrial Complex With P'R Prolongation Indicates Multiple Atrioventricular Nodal Pathways
- Molecular and Structural Basis of the Arrhythmogenic Pulmonary Veins(Arrhythmia, Basic 1 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Molecular and Electrophysiological Differences in the L-type Ca^ Channel between the Atrium and the Ventricle in Rat Hearts(Arrhythmia, Basic 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Synergistic Effects of Risk Factors for Stroke and Atrial Fibrillation on Endocardium in Rat Atria(Arrhythmia, Basic (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-060 Circadian Variation of Paroxysmal Atrial Fibrillation : Eeffects of Antiarrhythmiac Drugs(ECG/Body Surface Potential Mapping/Holler 1 (A) : PJ10)(Poster Session (Japanese))
- PJ-485 Electrocardiographic Characteristics of Isolated Noncompaction Ventricular Myocardium in 190 Japanese Adult Patients(ECG/Body surface potential mapping/Holter(06)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circul
- Ambulatory Holter recordings in patients with atrioventricular nodal reentrant tachycardia : comparative study with electrophysiologic study
- Alcohol-induced electrical remodeling : effects of Na^+ channel blockade on the alcohol-induced paroxysmal atrial fibrillation
- Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2008) : Digest Version
- Heart failure with preserved versus reduced left ventricular systolic function : A prospective cohort of Shinken Database 2004-2005
- Clinical outcome after acute coronary syndrome in Japanese patients : An observational cohort study
- Prevalence and Prognosis of Patients With Atrial Fibrillation in Japan : A Prospective Cohort of Shinken Database 2004