Reduced Cardiac Function of Patients with Implantable Cardioverter-Defibrillator Shock; 3-Years Follow Up Study

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Background: Therapy with implantable cardioverter-defibrillator (ICD) improves survival among patients who were at risk for sudden cardiac death, however patients who received shocks for any arrhythmia had a substantially higher risk of death than patients not receiving any shocks. The purpose of this study was to investigate the long-term follow up of cardiac function who received ICD therapy. Methods: We retrospectively analyzed 13 patients received at least one ICD shock (Group 1) and 35 patients without any ICD shocks (Group 2) who underwent implantation of defibrillators between October 1999 and April 2008. Echocardiography was evaluated before and at 3 years after implantation of defibrillator. Results: At Baseline, left ventricular ejection fraction (LVEF) (Group 1 vs. Group 2, 46±16% vs. 52±14%, p=0.2) were not different between two groups. After 3 years, LVEF was significantly decreased in Group 1 compared to Group 2 (43±15% vs. 52±13%, p=0.04). All-cause death was observed in 2 patients in Group 1, and 3 patients in Group 2 (p=0.6). Re-hospitalization due to cardiac disease was observed more in Group 1 than Group 2 (8 vs. 8, p=0.02). Conclusion: Three years after implantation of defibrillators, reduced cardiac function was observed in patients with at least one shock of any types. The cardiac performance of patients receiving defibrillator shock may require further clarification.