Bepridil Might Be Useful to Restore Sinus Rhythm after Pulmonary Vein Isolation in Mildly Remodeled Persistent Atrial Fibrillation

スポンサーリンク

概要

• 論文の詳細を見る

• <B>Background:</B> Although early recurrence (ER) after PV isolation (PVI) in patients with persistent AF is often observed, optimal medical therapy of ER is still undetermined. <B>Objective:</B> The purpose of this study was to demonstrate the effect of bepridil for restoration of sinus rhythm (SR) after ER (ER: occurrence of AF or atrial tachycardia (AT) within 30 days after PVI). <B>Methods and Results:</B> We performed PVI for 77 patients with persistent AF (male 58 patients, 61±12 years old). ER was occurred in 38 cases (49%), for whom we administered bepridil to 25 (Bepridil-group), no anitiarrythmic drug to 12 (noAAD-group), amiodarone to 1. During follow-up periods (149±121 days), 13 patients (52%) obtained SR in Bepridil-group, while 3 patients (33%) obtained SR in noAAD-group. The cohort of SR restored in Bepridil-group showed smaller LA diameter (42 vs. 48 mm, p=0.04), shorter duration of persistent AF before PVI (357 vs. 1519 days, p=0.01), higher rate of either induction ofself-limited AF or non-induction of AF by CS burst pacing immediately after PVI (50% vs. 11%, p=0.01), and higher incidence for ER of not persistent but paroxysmal AF or AT (69% vs. 16%, p<0.01) than that of SR not restored. <B>Conclusion:</B> It is suggested that bepridil is useful for SR restoration in mildly remodeled persistent AF after PVI

著者

• Murakami Yoshimasa

  Division Of Cardiology Aichi Prefecture Cardiovascular And Respiratory Center

• SUZUKI Shin

  Division of Cardiology,Sakakibara Heart Institute

• Yoshida Takayuki

  Division Of Cardiology Nagoya City Moriyama Municipal Hospital

• Murakami Yoshimasa

  Division of Cardiology, Nagoya City East Medical Center

• Suzuki Shin

  Division of Cardiology, Nagoya City East Medical Center

関連論文

• Predictors of Congestive Heart Failure in Patients on Maintenance Hemodialysis
• Vagal Modification Can Also Help Prevent Late Recurrence of Atrial Fibrillation After Segmental Pulmonary Vein Isolation
• PJ-511 Preoperative eGFR and LVdP/dtmax Predict the Long-term Effectiveness of Cardiac Resynchronization Therapy(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-784 The Greater Efficacy of Extensive Encircling Pulmonary Vein Isolation for Persistent Atrial Fibrillation Than Individual Pulmonary Vein Antrum Isolation(Arrhythmia, therapy(17)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the J
• PJ-783 Catheter ablation for atrial fibrillation targeting atrial areas showing complex fractionated atrial electrogram after extensive ipsilateral pulmonary vein isolation(Arrhythmia, therapy(17)(A),Poster Session(Japanese),The 72nd Annual Scientific Mee
• PJ-695 Optimizing VV Delay by Three-Dimentional Echocardiography(Heart failure, clinical(19)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-599 Efficacy of Pulmonary Vein Isolation in Patients with Bradycardia-Tachycardia Syndrome(Arrhythmia, therapy(16)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-394 Sleep Apnea Syndrome May Play a Role in the Higher Incidence of Non-Pulmonary Vein Ectopic Beats Initiating Atrial Fibrillation(Arrhythmia, diagnosis/Pathophysiology/EPS(14)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japa
• PJ-316 Acute Hemodynamic Effects of V-V Delay Optimization in Cardiac Resynchronization Therapy(Heart failure, clinical(15)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-315 Absolute Value of LVdP/dtmax during Intrinsic Rhythm and CRT at Baseline Predict the Long-term Effectiveness of CRT(Heart failure, clinical(15)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-284 Behavior of Atrial Premature Beats Triggering the Recurrences of Atrial Fibrillation After Pulmonary Vein Isolation(ECG/Body surface potential mapping/Holter(05)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circula
• PJ-221 Should Combined Resynchronization and Defibrillator Therapy be Indicated in All Japanese CRT Candidates without Ventricular Arrhythmias?(Arrhythmia, therapy(24)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulat
• PE-147 Efficacy of catheter ablation of atrial fibrillation in patients with hypertrophic cardiomyopathy(Arrhythmia, therapy(12)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-075 Does Cardiac Resynchronization Therapy Improve Heart Rate-Dependent Ventricular Performance in Patients with Impaired Cardiac Function and Left Bundle Branch Block?(Cardiac function, basic/clinical(02)(M),Oral Presentation(Japanese),The 72nd Annual
• 3 Significance of Acute Hemodynamic Study Using Catheter-tip Manometer after Cardiac Resynchronization Therapy(Is assessment of mechanical dyssynchrony necessary in determining CRT indication?,Controversy 4 (C-4) (M),Special Program,The 72nd Annual Scient
• Efficacy of Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation Patients With a Brugada Electrocardiogram
• Pulmonary Vein Antrum Not Always Coaxial to the Pulmonary Vein : A Dimensional Pitfall to the Circumferential Isolation Technique
• PJ-411 Relationship between Early Recurrence within Three Days from Successful Extensive Encircling Pulmonary Vein Isolation for Atrial Fibrillation and Long-term Recurrence(Arrhythmia, therapy-21, The 71st Annual Scientific Meeting of the Japanese Circul
• PJ-403 Clinical Effectiveness of CRT for Moderate to Severe Mitral Regurgitation in Patients with HF and IVCD(Valvular herat disease/Pericarditis/Cardiac tumor-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-376 Midterm Outcome of Upgrading from RV Pacing to CRT in Previously Paced Patients with Severe HF and LV Systolic Dysfunction(Heart failure, clinical-10, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-375 Clinical Effectiveness of CRT in Patients with NYHA Class II Heart Failure and IVCD(Heart failure, clinical-10, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-040 Acute Pulmonary Vein (PV) Stenosis after PV Isolation for Atrial Fibrillation (AF) Evaluated by Intra Cardiac Echocardiography (ICE)(Arrhythmia, diagnosis/pathophysiology/EPS-09, The 71st Annual Scientific Meeting of the Japanese Circulation Societ
• A Combined Therapy Using Encircling Pulmonary Vein Isolation and Supplemental Segmental Ostial Isolation for the Treatment of Atrial Fibrillation
• Accumulation of trehalose in response to desiccation and salt stress in the terrestrial cyanobacterium Nostoc commune
• PJ-227 Evidence for Impaired Cardiac Autonomic Nerve Reflex during Balloon Coronary Occlusion in Patients with Diabetes(Autonomic nervous system-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-779 Predictive Value of Surrogate Markers of Effective Reperfusion on Greater Myocardial Salvage in Patients with Acute Myocardial Infarction(Myocardial ischemia-reperfusion, basic/clinical-6 (IHD) PJ136,Poster Session (Japanese),The 70th Anniversary A
• The Distal Protection During Primary Percutaneous Coronary Intervention Alleviates the Adverse Effects of Large Thrombus Burden on Myocardial Reperfusion
• Distal Protection during Primary Percutaneous Coronary Intervention Improves Myocardial Reperfusion of Infarct-Related Artery with High-Burden Thrombus Formation(Myocardial Ischemia-reperfusion, Clinical 2 (IHD), The 69th Annual Scientific Meeting of the
• INTRACORONARY ULTRASOUND ASSESSMENT OF CORONARY STENTS
• OE-184 Delayed Stent Fracture and Restenosis after Successful Implantation of Sirolimus-Eluting Stent(Coronary revascularization, PCI-02, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-570 The Impact of Immediate Elastic Recoil on Late Restenosis After Balloon Angioplasty in Small Coronary Arteries(Restenosis after Angioplasty, Basic/Clinical 7 (IHD) : PJ95)(Poster Session (Japanese))
• OJ-115 The Long-Term Outcomes of Cutting Balloon Angioplasty With Provisional Stenting in Small Coronary Arteries : A Comparison With Primary Stenting(Coronary Revascularization, PICA/Stent/DCA/Rotablator/New Device 2 (IHD) : OJ14)(Oral Presentation (Japa
• Vagal Modification can be a Valid Predictor of Late Recurrence of Paroxysmal Atrial Fibrillation Independent of the Pulmonary Vein Isolation Technique
• PE-554 Clinical Utility of Left Atrial Volume in Coronary Heart Disease Patients with Mildly Elevated E/E' : Comparison with PAWP and BNP(PE093,Echo/Doppler (Others) (I),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulati
• PJ-327 Advanced Glycation End-Product, Pentosidine, is an Independent Determinant of Ankle-Brachial Index in Men(PJ055,Peripheral Circulation/Vascular Disease (Pathophysiology, Basic) 2 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of T
• PJ-722 Circulating Malondialdehyde-Modified Low-Density Lipoprotein is Strongly Associated with Very Small Low-Density Lipoprotein Cholesterol Levels in Healthy Men(Lipid disorders(04)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the
• PE-432 Very small Low-Density Lipoprotein Cholesterol Level is a Determinant of Arterial Stiffness in Men with Impaired Glucose Metabolism(Hypertension, clinical(05)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation
• PJ-416 Circadian Variation of Plasma Catecholamine and Pulse Wave Velocity in Hypertensive Patients, compared with Normotensive Subjects(Atherosclerosis, clinical(11)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circula
• Antiarrhythmic efficacy of dipyridamole in treatment of reperfusion arrhythmias : Evidence for cAMP-mediated triggered activity as a mechanism responsible for reperfusion arrhythmias
• OJ-128 Coronary Artery Calcification Detected by Electron bean Computed Tomography in Old-aged Subjects(CT / DSA-04, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-534 Association between Intimal Medial Thickness of the Carotid Arteries and Coronary Artery Calcification(CT/DSA-7 (I) PJ90,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-237 Can Crochetage Pattern Identify Presence of Patent Foramen Ovale in Patients with Atrial Fibrillation?(ECG/Body surface potential mapping/Holter-7, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-062 Can Further Vagal Modification be Achieved by a Superior Vena Cava Isolation Added to the Pulmonary Vein Isolation?(Arrhythmia, therapy-16, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-061 The Predictor of Long-Term Success in Patients with Early Recurrence of Atrial Fibrillation After Pulmonary Vein Isolation(Arrhythmia, therapy-16, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-034 Implication of Inducible Left Atrial Tachycardia after Pulmonary Vein Isolation for Atrial Fibrillation(Arrhythmia, therapy-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OE-066 Autonomic Nervous Remodeling Toward a Vagal Tonic State Could be Caused by the Perpetuation of Atrial Fibrillation(Arrhythmia, diagnosis/pathophysiology/EPS-01, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-614 Characteristics of Myocardial Fibers and Network of Superior Vena Cava in Paroxysmal Atrial Fibrillation(Arrhythmia, diagnosis/pathophysiology/EPS-14 (A) PJ103,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese
• PJ-610 Significant Reduction in the Plasma ANP and BNP Levels after Radiofrequency Ablation of Atrial Fibrillation(Arrhythmia, diagnosis/pathophysiology/EPS-14 (A) PJ103,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japan
• -P607- INTRAVASCULAR ULTRASOUND EVALUATION OF PALMAZ-SCHATZ STENT:RELATIONSHIP BETWEEN BALLOON PRESSURE AND CORONARY ARTERIAL CALCIFICATION.(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• Radiofrequency Catheter Ablation during Sustained Atrial Fibrillation : Efficacy of a Multielectrode Basket Catheter for Mapping and Ablating Trigger Points
• Difference in the Electrophysiological Characteristics of Two Different Types of Electrical Activities within Pulmonary Veins
• Electrophysiological Characteristics and Results of Superior Vena Cava (SVC) Isolation : Comparison with Pulmonary Vein (PV) Isolation
• Radiofrequency Catheter Ablation of Focal Atrial Fibrillation Originating from the left Pulmonary Veins with a Common Ostium
• Computerized Three-Dimensional Potential Mapping with a Multielectrode Basket Catheter Can Be Useful for Pulmonary Vein Electrical Disconnection
• P265 RELATION BETWEEN PLASMA BRAIN NATRIURETIC PEPTIDE CONCENTRATION AND RIGHT VENTRICULAR VOLUME IN PATIENTS WITH CHRONIC PULMONARY DISEASE : OBSERVATION BY ELECTRON BEAM TOMOGRAPHY
• 表彰論文 Computerized three-dimensional potential mapping with a multielectrode basket catheter can be useful for pulmonary vein electrical disconnection
• THE EFFECT OF CIRCADIAN RHYTHM. SEASON AND METEOROLOGIOCAL FACTORS ON ONSET OF ACUTE MYOCARDIAL INFARCTION
• PJ-166 Can Additional RF Deliveries after Successful Pulmonary Vein Isolation Reduce the Recurrence of Atrial Fibrillation?(Arrhythmia, Non-Pharmacological Therapy 6 (A) : PJ28)(Poster Session (Japanese))
• PJ-162 Low Incidence of Recovery of Atrio-Venous Electrical Connection after Superior Vena Cava Isolation : Comparison with Pulmonary Vein Isolation(Arrhythmia, Non-Pharmacological Therapy 5 (A) : PJ27)(Poster Session (Japanese))
• PJ-160 Higher-Power RF Ablation with Guidance Using Basket Catheter Does not Increase Incidence of Pulmonary Vein (PV) Stenosis after PV Isolation.(Arrhythmia, Non-Pharmacological Therapy 5 (A) : PJ27)(Poster Session (Japanese))
• PJ-011 Left Atrial Macroreentrant Tachycardia can Mimic the Electrocardiographic Characteristics of Atrial Flutter after Linear Ablation of Cavo-Tricuspid Annulus(Arrhythmia, Diagnosis/Pathophysiology/EPS 4 (A): PJ2)(Poster Session (Japanese))
• Pulmonary Vein Isolation in Patients With Paroxysmal Atrial Fibrillation After Direct Suture Closure of Congenital Atrial Septal Defect
• ROLE OF TREHALOSE IN STRESS RESPONSE OF THE TERRESTRIAL CYANOBACTERIUM NOSTOC COMMUNE
• Adrenocorticotropic hormone-independent bilateral macronodular adrenocortical hyperplasia associated with Cushing's syndrome
• Plasma Brain Natriuretic Peptide Level After Hybrid Therapy With Pulmonary Vein Isolation and Antiarrhythmic Drugs for Atrial Fibrillation
• Noninvasive Detection of Coronary Artery Bypass Graft Patency by Intravenous Electron Beam Computed Tomographic Angiography
• Esophageal Leads Can be Useful for Determining the Strategy of PV Ablation to Avoid Complications Associated with the Esophagus(Arrhythmia, Non-pharmacological Therapy 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Circumferential Pulmonary Vein Isolation is More Effective for Curing Paroxysmal Atrial Fibrillation than Segmental Pulmonary Vein Ostial Isolation(Arrhythmia, Non-pharmacological Therapy 10 (A), The 69th Annual Scientific Meeting of the Japanese Circulat
• Circumferential PV Isolation Significantly Reduces Difference in AF Recurrence between Persistent and Paroxysmal AF as Compared to Segmental PV Isolation(Arrhythmia, Non-pharmacological Therapy 10 (A), The 69th Annual Scientific Meeting of the Japanese Ci
• Electrophysiological Pulmonary Vein Antrum Ablation with Multielectrode Basket-catheter is Effective for Curing AF : Efficacy of Minimally Extensive Pulmonary Vein Isolation(Arrhythmia, Non-pharmacological Therapy 5 (A), The 69th Annual Scientific Meeting
• FRS-032 How Does Triggered Ectopic Activity Induce Atrial Fibrillation within the Pulmonary Veins?(Arrhythmia-Clinical : Advances in Diagnosis and Management (A) : FRS5)(Featured Research Session (English))
• Radiofrequency Catheter Ablation Can Be a Very Effective Therapy in the Properly Selected AF Patients by Improving Quality of Life
• Acute Effect of Sodium Nitroprusside on Microvascular Dysfunction in Patients Who Underwent Percutaneous Coronary Intervention for Acute ST-segment Elevation Myocardial Infarction
• Bepridil Might Be Useful to Restore Sinus Rhythm after Pulmonary Vein Isolation in Mildly Remodeled Persistent Atrial Fibrillation
• Persistent Electrical Scar in the Atrium Evaluated on Voltage Mapping With a CARTO System in Suspected Acute Myocarditis

もっと見る 閉じる

スポンサーリンク