The Utility of the CHA2DS2-VASc Score to Predict the Left Atrial Appendage Sludge/Thrombus in Patients with Atrial Fibrillation

概要

論文の詳細を見る
Purpose: The aim of this study was to assess what parameters predict the left atrial (LA)/LA appendage (LAA) sludge/thrombus on transesophageal echocardiography (TEE) in patients with atrial fibrillation (AF). Methods and Results: Total two-hundred and forty-eight patients (age 66±12 years, BNP 150±220, PT-INR 2.2±0.9, CHADS2 1.67±1.24, CHA2DS2-VASc score 2.81±1.87) underwent TEE screening studies between January 2007 and December 2010 in our hospital. Almost all the cases were seen prior to electrical defibrillation. PAF/PAT was observed in 69 and 10 patients, respectively and CAF in 142. The prevalence of LA/LAA thrombi, sludge, and spontaneous echo contrast (SEC) was 11%, 7%, and 24%, respectively. Compared with the normal/spontaneous echo contrast (SEC) patients, the LA/LAA sludge/thrombus patients had a higher mean CHA2DS2-VASc score (3.2±1.82 vs. 2.6±1.83 P<0.05), larger LA volume (47±7 vs. 42±8 P<0.01) and smaller LA appendage velocity (0.37±0.17 vs. 0.51±0.21 P<0.05), and it was not significantly correlated with the CHADS2 score (1.9±1.1 vs. 1.6±1.2 P=0.07). Conclusion: For the clinical parameters, the CHA2DS2Vasc score was significantly related to the prevalence of LA/LAA sludge/thrombi in patients with AF.