Restoration of Impaired Cardiac Function in Patients with Dilated Cardiomyopathy after the Radiofrequency Catheter Ablation of Long-Standing Persistent Atrial Fibrillation with Adequate Ventricular Rate Control
スポンサーリンク
概要
- 論文の詳細を見る
Tachycardia induced cardiomyopathy is a well-known form of reversible cardiac dysfunction; however, the effect of maintaining sinus rhythm by a radiofrequency catheter ablation (RFCA) in patients with impaired cardiac function and adequately rate-controlled atrial fibrillation (AF) is unclear. Six patients (54±9 years old, 5 men) with drug-resistant persistent AF (lasting 21±14 months) combined with dilated cardiomyopathy (DCM) had suffered from heart failure for more than one year in spite of an adequate ventricular rate control (<90 bpm) and intensive medications including angiotensin converting enzyme inhibitors, angiotensin receptor blockers, beta-blockers, diuretics, and an amiodarone. All patients underwent the RFCA of AF and were maintained in sinus rhythm during a mean follow-up period of 14±19 months. The left ventricular ejection fraction increased from 32±8% to 60±8%, the left atrial diameter decreased from 50±8 mm to 48±10 mm, and the BNP decreased from 302±166 pg/ml to 56±79 pg/ml at the end of the follow-up period. The RFCA of AF may provide a chance to restore an impaired cardiac function in patients who have already diagnosed as DCM with adequately rate-controlled persistent AF.
著者
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Tada Hiroshi
Cardiology Department of Internal Medicine, Univercity of Tsukuba Graduate School of Comprehensive H
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Igarashi Miyako
Cardiovascular division, Graduate School of Comprehensive Human Sciences, University of Tsukuba
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Yoshida Kentaro
Cardiology Department of Internal Medicine, University of Tsukuba Graduate School of Comprehensive H
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Yamasaki Hiro
Cardiology Department Of Internal Medicine University Of Tsukuba Graduate School Of Comprehensive Hu
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Machino Takeshi
Cardiology Department Of Internal Medicine University Of Tsukuba Graduate School Of Comprehensive Hu
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Sekiguchi Yukio
Cardiology Department Of Internal Medicine University Of Tsukuba Graduate School Of Comprehensive Hu
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Ishizu Tomoko
Cardiovascular Division Graduate School Of Comprehensive Human Sciences University Of Tsukuba
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Aonuma Kazutaka
Cardiology Department Of Internal Medicine University Of Tsukuba Graduate School Of Comprehensive Hu
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Kuroki Kenji
Cardiology Department Of Internal Medicine University Of Tsukuba Graduate School Of Comprehensive Hu
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Nakano Emi
Cardiovascular Division Kawasaki Municipal Tama Hospital
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Ishizu Tomoko
Cardiovascular Division, Graduate School of Comprehensive Human Sciences, University of Tsukuba
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Yui Yoshiaki
Cardiovascular Division, Graduate School of Comprehensive Human Sciences, University of Tsukuba
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Yukio Seo
Cardiovascular Division, Graduate School of Comprehensive Human Sciences, University of Tsukuba
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Yamasaki Hiro
Cardiovascular Division, Graduate School of Comprehensive Human Sciences, University of Tsukuba
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Igarashi Miyako
Cardiovascular Division, Faculty of Medicine, University of Tsukuba
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